Seminar: Synthetic chemistry/Molecular biology | Feb 15 | 2 p.m.-3 p.m. | Zoom
Renata Perlikowska, Department of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Poland
Synthesis and pharmacological evaluation of novel opioid peptide analogs
Host: Helena Gaspar
Zoom: https://videoconf-colibri.zoom.us/j/98061448183
ID: 980 6144 8183
Pass: 844416
A growing body of evidence suggests that peptides derived from natural materials or their synthetic analogs are good candidates for therapeutic agents. They presented a broad spectrum of activities and abilities to act through diverse mechanisms of action. Biologically active peptides have many properties, including antioxidant, antimicrobial, antiinflammatory, and immunomodulatory effects. In my research group, we proposed short synthetic peptides as the analogs of endomorphin or rubiscolins, that can be remodeled in numerous ways to have desired features, such as increased stability, as well as selectivity towards a specific receptor, and finally, better biological activity.